1 box of 2 blisters.
Orlistat is a reversible inhibitor of lipases. It exerts its therapeutic activity in the lumen of the stomach and small intestine by forming a covalent bond with the active serine residue site of gastric and pancreatic lipases. The inactivated enzymes are thus unavailable to hydrolyze dietary fat in the form of triglycerides into absorbable free fatty acids and monoglycerides. As undigested triglycerides are not absorbed, the resulting caloric deficit may have a positive effect on weight control. Systemic absorption of the drug is therefore not needed for activity.
Each Orlistat STADA® 60 mg capsule contains:
Orlistat (pellets)…………….……….....60 mg
Each Orlistat STADA® 120 mg capsule contains
Orlistat (pellets)……………………….120 mg
Dosage and Administration:
Management of obesity and weight regain in adults and adolescents 12 years of age and older: 120 mg 3 times daily with each main meal containing fat.
Over weight adults 18 years of age and older: 60 mg 3 times daily with each meal containing fat.
The capsule should be taken with water immediately before, during or up to 1 hour after each main meal. If a meal is missed or contains no fat, the dose of orlistat should be omitted.
Dosage exceeding 3 times daily have not been shown to provide additional benefit.
If patients have been unable to lose weight after 12 weeks of treatment with Orlistat STADA®, they should consult their doctor or a pharmacist. It may be necessary to discontinue treatment.
Diet and exercise are important parts of a weight loss programme. It is recommended that a diet and exercise programme is started before beginning treatment with Orlistat STADA®.
The patient should be on a nutritionally balanced, mildly hypocaloric diet that contains approximately 30% of calories from fat. The daily intake of fat, carbohydrate and protein should be distributed over three main meals.
Chronic malabsorption syndrome or cholestasis.
Known hypersensitivity to orlistat or any ingredient in the formulation.
Orlistat should be given with caution to patients with a history of hyperoxaluria or calcium oxalate nephrolithiasis. Adjustments to dosage of hypoglycaemics may be necessary in patients with type II diabetes because of improved metabolic control after weight loss in these patients. Supplements of fat-soluble vitamins may be necessary during long-term therapy, but they should be taken at least 2 hours before or after an orlistat dose or at bedtime. Hormonal contraceptive failure may occur in the event of severe diarrhoea with orlistat, and patients are advised to use an additional contraceptive method.
The information on this page is not intended to be a subsitute for professional medical advise.
|Brand:Stada||Country/Region of Manufacture:Viet Nam|